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H. Arnouk 's Advancements in Tumor Immunotherapy, Cancer Vaccines PDF

By H. Arnouk

ISBN-10: 9533079983

ISBN-13: 9789533079981

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Extra info for Advancements in Tumor Immunotherapy, Cancer Vaccines

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2008). , 2006). An active multi-center trial is evaluating progressionfree survival in 80 patients with metastatic castration-resistant prostate cancer receiving 10 cycles of docetaxel with or without TroVax (Oxford BioMedica & MedSource). This trial is expected to conclude in 2016. Vaccine and Cancer Therapy for Genitourinary Tumors 25 More recently in pre-clinical murine models, a vaccine has been developed that destroys prostate cancer in by producing antigens that attack the prostate tumor cells.

Of these 27 patients, 14 were treated with TroVax alone and 13 received a combination of TroVax and granulocyte macrophage colony-stimulating factor. Of the 24 evaluable patients, all achieved a 5T4-specific antibody response. No grade 3 or 4 toxicities were observed, and minor incidences of myalgia, bone discomfort, lowgrade temperature elevation, and injection site irritation were experienced by patients. , 2008). , 2006). An active multi-center trial is evaluating progressionfree survival in 80 patients with metastatic castration-resistant prostate cancer receiving 10 cycles of docetaxel with or without TroVax (Oxford BioMedica & MedSource).

Journal of Clinical Oncology, Vol. 28, No. 7, (March 2010), pp. , & Kim-Schulze S. (2009). Phase II trial of Modified Vaccinia Ankara (MVA) virus expressing 5T4 and high dose Interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma. , Vol. 7, No. 7:2, (January 2009). , & Vile, R. (2011). Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors. , & Rubben H. (1996). A randomized multicenter trial of adjuvant therapy in superficial bladder cancer: transurethral resection plus bacillus Calmette-Guerin.

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Advancements in Tumor Immunotherapy, Cancer Vaccines by H. Arnouk


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