By Gabriel Oniscu, John Forsythe, John Fung
Offers transplant pros with a step-wise method of belly organ retrieval and bench surgical procedure, illustrating complicated anatomical events and supplying perform issues and choice algorithms. A go-to reference for transplant surgeons, trainees and fellows, in addition to for different execs focused on stomach organ transplantation.
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Extra resources for Abdominal Organ Retrieval and Transplantation Bench Surgery
18 Wahlberg JA, Love R, Landegaard L, et al. 72-hour preservation of the canine pancreas. Transplantation 1987; 43:5–8. 19 Bonventre JV, Cheung JY. Effects of metabolic acidosis on viability of cells exposed to anoxia. Am J Physiol 1985; 249:C149–59. 20 Kosieradzki M, Kuczynska J, Piwowarska J, et al. Prognostic significance of free radicals: mediated injury occurring in the kidney donor. Transplantation 2003; 75(8):1221–7. 21 Byrne AT, Johnson AH. Lipid peroxidation. In: Grace P, Mathie R (eds) Ischaemia-reperfusion injury.
Aggressive pharmacologic donor management results in more transplanted organs. Transplantation 2003; 75(4):482–7. 25 Feng S. Donor intervention and organ preservation: where is the science and what are the obstacles? Am J Transplant 2010; 10(5):1155–62. 26 Formanek M, Schöffski O. Difficulties with the organ donation process in small hospitals in Germany. Transplant Proc 2010; 42(5):1445–8. 27 Venkateswaran RV, Steeds RP, Quinn DW, et al. The haemodynamic effects of adjunctive hormone therapy in potential heart donors: a prospective randomized double-blind factorially designed controlled trial.
Brainstem death is also associated with an active inflammatory response, with elevated levels of proinflammatory cytokines and upregulation of receptors in target organs. Although this may be due to associated trauma or critical illness, brainstem death itself may trigger this response. The inflammatory response is maintained or amplified by the physiological changes related to brainstem death [16,17,18]. This affects all organs and is associated with measurable organ damage in the donor, and subsequent poor function and increased risk of graft loss in recipients.
Abdominal Organ Retrieval and Transplantation Bench Surgery by Gabriel Oniscu, John Forsythe, John Fung